Perforin Workshop

Perforin: From Basic Biology to Disease

Date: Monday 24th September
Time: 9:00am - 4:00pm
Location: Salone Grollo

Immune surveillance of viral infections and cancer is a fundamental physiological process that is essential for the survival of an organism.
Cytotoxic lymphocytes play a key role in maintaining immune homoeostasis by eliminating infected or cancerous cells. They achieve this by recognising the target and delivering cytotoxic effector molecules, a pore-forming protein perforin and pro-apoptotic serine proteases, granzymes. The loss of perforin is detrimental for an organism as it results in a fatal immune dysregulation.
Our understanding of these processes has been greatly enhanced by a combination of biochemistry, cell biology, genetics and immunology approaches, but the field of perforin and cytotoxic lymphocyte biology keeps surprising us with new developments and paradigms.
This workshop aims to bring together biochemists, cell biologists and immunologists to create a multidisciplinary forum for exchanging ideas and creating collaborations in this exciting field.

Perforin Workshop Speakers

Speakers subject to change. Please check back for updates.